https://physiologicinstruments.com/blogs/news/the-nsaid-glafenine-rescues-class-2-cftr-mutants-via-cyclooxygenase-2-inhibition-of-the-arachidonic-acid-pathway 2025-12-15T09:11:01-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/41598_2022_8661_Fig2_HTML_720979e1-8cab-426c-9cef-209437f07f72.webp?v=1765807861 The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway https://physiologicinstruments.com/blogs/news/exon-skipping-antisense-oligonucleotides-for-cystic-fibrosis-therapy 2025-01-15T14:43:44-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/pnas.2114858118fig01.jpg?v=1736970224 Exon-skipping antisense oligonucleotides for cystic fibrosis therapy https://physiologicinstruments.com/blogs/news/restraint-stress-in-hypertensive-rats-activates-the-intestinal-macrophages-and-reduces-intestinal-barrier-accompanied-by-intestinal-flora-dysbiosis 2025-01-15T14:43:42-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/JIR_A_294630_O_F0007g.jpg?v=1736970222 Restraint Stress in Hypertensive Rats Activates the Intestinal Macrophages and Reduces Intestinal Barrier Accompanied by Intestinal Flora Dysbiosis https://physiologicinstruments.com/blogs/news/abrupt-suspension-of-probiotics-administration-may-increase-host-pathogen-susceptibility-by-inducing-gut-dysbiosis 2025-11-18T12:02:27-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/41598_2016_Article_BFsrep23214_Fig6_HTML_cdddb709-dbec-41df-81c0-007b4d10c0c6.jpg?v=1763485347 Abrupt suspension of probiotics administration may increase host pathogen susceptibility by inducing gut dysbiosis https://physiologicinstruments.com/blogs/informational/what-is-a-voltage-current-clamp 2025-12-15T09:45:37-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Voltage-Current-Clamp-for-Ussing-Chamber-Systems_522009ca-68c8-4faf-9f68-f3e4900d1680.jpg?v=1765809937 What Are Voltage / Current Clamps? What is a Voltage Current Clamp? https://physiologicinstruments.com/blogs/informational/what-is-cystic-fibrosis 2025-08-11T12:08:05-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/What-is-cystic-fibrosis_bea229aa-3e0b-4d99-aafb-efb07e2844be.jpg?v=1754928485 What is Cystic Fibrosis? What is cystic fibrosis https://physiologicinstruments.com/blogs/informational/ussing-s-little-chamber-60-years-old-and-counting 2025-01-15T14:43:37-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/dsc_0892_1_1_1_2.jpg?v=1736970217 Ussing’s “little chamber”: 60 years+ old and counting https://physiologicinstruments.com/blogs/news/how-do-ussing-chambers-work-a-step-by-step-guide 2025-08-12T14:38:03-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/ussing-chamber-system-physiologic-instruments_881ee551-766f-4883-80c3-49cf0ee40aef.png?v=1755023883 How Do Ussing Chambers Work? A Step-by-Step Guide How Do Ussing Chambers Work https://physiologicinstruments.com/blogs/news/ussing-chamber-systems 2025-06-27T15:45:32-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/drug-screening.jpg?v=1751053532 Ussing Chamber Systems | EasyMount Ussing Systems Image of Ussing Chamber Systems connected together. In this image is multiple eight channel ussing chamber systems with a laboratory technician administering drug to each side of the ussing chamber. https://physiologicinstruments.com/blogs/news/wie-funktionieren-ussing-kammern-eine-schritt-fur-schritt-anleitung 2025-10-22T14:39:23-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/EasyMount-Ussing-Chamber-System_e9d2d5dc-e2b3-4f50-a8dc-eebbb5611783.jpg?v=1761158363 Wie funktionieren Ussing-Kammern? Eine Schritt-für-Schritt-Anleitung Wie funktionieren Ussing-Kammern? Eine Schritt-für-Schritt-Anleitung https://physiologicinstruments.com/blogs/news/how-the-ussing-chamber-system-accelerates-epithelial-research 2025-11-18T12:20:44-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Unlocking_Barrier_Function_Physiologic_Instruments.png?v=1763486444 How the Ussing Chamber System Accelerates Epithelial Research Barrier Function | How Ussing Chamber Systems Accelerates Epithelial Research https://physiologicinstruments.com/blogs/news/what-is-the-benchmark-tool-for-cystic-fibrosis-ion-transport-research 2025-11-18T12:00:21-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Tools_for_Cystic_Fibrosis_Ion_Transport_Research_Ussing_Chamber_b1e3e699-6025-424e-af7d-076a86fe585e.jpg?v=1763485221 What is the Benchmark Tool for Cystic Fibrosis Ion Transport Research? Cystic Fibrosis Ion Transport Research Tools - The Ussing Chamber https://physiologicinstruments.com/blogs/news/physiological-instruments 2025-08-11T14:39:14-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Physiological_Instruments_vs_Physiologic_Instruments.png?v=1754937554 What Are Physiological Instruments and Why Physiologic Instruments Leads the Field Physiological Instruments vs Physiologic Instruments https://physiologicinstruments.com/blogs/news/ussing-chamber-system-price-cost 2025-12-29T16:19:26-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Ussing-Chamber-System-Costs_e1b6591f-f900-4480-92c9-08f03b9e7ad7.jpg?v=1767043166 Buying a Ussing Chamber System: Cost & Budget Guide Ussing Chamber System Cost, Ussing Chamber Price https://physiologicinstruments.com/blogs/informational/guide-to-intestinal-permeability-assay-equipment 2025-08-11T16:26:42-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Intestinal_Barrier_Function_InVitro_6c44e60f-890a-4750-aada-5e4f373cd9a9.png?v=1754944002 Guide to Intestinal Permeability Assay Equipment Intestinal Barrier Function https://physiologicinstruments.com/blogs/informational/the-complete-ussing-chamber-guide-reddit 2026-06-30T09:39:28-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/The-Complete-Ussing-Chamber-Guide.png?v=1782826768 The Complete Ussing Chamber Guide - also via Reddit The Complete Ussing Chamber Guide https://physiologicinstruments.com/blogs/news/complete-ussing-chamber-guide 2025-11-18T17:14:12-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Complete_Ussing_Chamber_Guide_80d38816-acbf-47c3-8d5d-bd38d5e279c6.png?v=1763504052 Complete Ussing Chamber Guide The Complete Ussing Chamber Guide - Protocols, Measuring Tips, and Troubleshooting https://physiologicinstruments.com/blogs/news/easymount-ussing-chambers-featured-in-cystic-fibrosis-research-news 2025-11-18T12:01:05-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/CFTR_Activity.png?v=1763485265 EasyMount® Ussing Chambers Featured in Cystic Fibrosis Research News Graph illustrating CFTR ion transport activity with short-circuit current measurements in an EasyMount Ussing Chamber experiment https://physiologicinstruments.com/blogs/news/easymount-ussing-chambers-enable-breakthrough-in-cystic-fibrosis-drug-research-f508del-cftr 2025-08-18T09:44:39-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Peptide_CIGB_552_Enhances_CFTR.png?v=1755524679 EasyMount® Ussing Chambers Enable Breakthrough in Cystic Fibrosis Drug Research Graph showing increased CFTR activity measured as short-circuit current using EasyMount Ussing Chambers in cystic fibrosis research https://physiologicinstruments.com/blogs/news/easymount%C2%AE-ussing-chamber-systems-from-physiologic-instruments-drive-advances-in-cystic-fibrosis-research 2025-08-18T16:40:16-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Physiologic_Instruments_VX-770_forskolin.png?v=1755549616 EasyMount® Ussing Chamber Systems from Physiologic Instruments Drive Advances in Cystic Fibrosis Research EasyMount Ussing Chamber System measuring CFTR chloride channel activity in cystic fibrosis research, showing forskolin-stimulated short-circuit current data alongside product image from Physiologic Instruments https://physiologicinstruments.com/blogs/news/guide-to-reproducible-intestinal-current-measurement-with-the-easymount-p2400 2025-09-16T13:55:14-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Intestinal_Current_Measurement_with_EasyMount_Ussing_Chamber.png?v=1758045314 From Biopsy to Bench: A PI’s Guide to Reproducible ICM with the EasyMount P2400 https://physiologicinstruments.com/blogs/news/compare-ussing-chamber-systems-easymount-vs-scientific-instruments-ussing-chambers 2025-09-15T16:51:38-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Pi_vs_Si.png?v=1757969498 Compare Ussing Chamber Systems: EasyMount vs. Scientific Instruments https://physiologicinstruments.com/blogs/news/scientific-instruments-ussing-chamber-comparison 2025-09-16T11:35:07-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Scientific_Instruments_Ussing_Chamber_53c20820-70b6-4c4a-b09b-15b64ee11d24.jpg?v=1758036907 5 Key Features in a Scientific Instruments Ussing Chamber Infographic comparing Scientific Instruments Ussing Chamber and Physiologic Instruments EasyMount Chamber https://physiologicinstruments.com/blogs/news/5-hauptmerkmale-einer-scientific-instruments-ussing-kammer 2025-11-18T12:02:14-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Scientific_Instruments_Ussing_Chamber_439b88e9-a00a-4bbc-8f2f-af18ffbe20de.jpg?v=1763485334 5 Hauptmerkmale einer Scientific Instruments Ussing-Kammer Infografik zum Vergleich der Scientific Instruments Ussing-Kammer und der Physiologic Instruments EasyMount-Kammer https://physiologicinstruments.com/blogs/news/wie-funktionieren-ussing-kammern-eine-schritt-fuer-schritt-anleitung-in-deutschland 2025-09-17T16:21:09-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Ussing-Chamber-Systems_ed4a89db-5b63-4037-92b1-e408d6c859bb.webp?v=1758140469 Wie funktionieren Ussing-Kammern? Eine Schritt-für-Schritt-Anleitung Wie funktionieren Ussing-Kammern? https://physiologicinstruments.com/blogs/news/cftrdele2ins182-ussing-chamber-research-breakthrough 2025-10-01T15:50:18-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/CFTR-Research-Breakthrough.png?v=1759348218 Breakthrough CFTR Study Uses Physiologic Instruments Ussing Chamber to Reveal New Therapeutic Pathways https://physiologicinstruments.com/blogs/news/ussing-chamber-the-complete-guide-principles-protocols-troubleshooting 2025-11-18T12:01:52-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Ussing_Chamber_Complete_Guide_680d8fcc-1874-4fe2-ae1f-da02f9f7e13f.jpg?v=1763485312 Ussing Chamber: The Complete Guide (Principles, Protocols, Troubleshooting & Product Selector) Ussing Chamber: The Complete Guide https://physiologicinstruments.com/blogs/news/voltage-clamp-explained 2025-11-18T12:03:52-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/ChatGPT_Image_Oct_8_2025_02_06_02_PM.png?v=1763485432 Voltage Clamp Explained: Principles, Applications, and How It Works Voltage clamp experiment diagram showing voltage and current electrodes, ion channel in a cell membrane, and amplifier controlling membrane potential and measuring ionic currents. https://physiologicinstruments.com/blogs/news/ussing-chamber-experiment-explained 2025-10-09T11:43:23-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Ussing_Chamber_Experiment_Explained_How_Scientists_Measure_Epithelial_Ion_Transport_8204befd-184e-4f8b-9c58-4b219846ba53.jpg?v=1760024603 Ussing Chamber Experiment Explained: How Scientists Measure Epithelial Ion Transport Ussing Chamber Experiment Explained: How Scientists Measure Epithelial Ion Transport https://physiologicinstruments.com/blogs/news/ussing-chamber-setup-calibration 2025-11-18T12:06:15-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Ussing-Chamber-Setup-_-Calibration-A-Complete-Ussing-Chamber-Setup-EM8_bfd25ad9-d5ba-42cb-94a6-c8f0ce39350f.jpg?v=1763485575 Ussing Chamber Setup & Calibration: TEER, Isc, and CFTR Assay Basics (with Troubleshooting) Ussing Chamber Setup & Calibration: TEER, Isc, and CFTR Assay Basics (with Troubleshooting) https://physiologicinstruments.com/blogs/news/why-is-my-isc-unstable-ussing-chamber-drift-noise-baseline-fixes 2025-10-10T14:44:21-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Ussing-Chamber-drift-Why-is-my-Isc-unstable_ff884983-5a26-4d04-9eaf-50ca2ef20b28.jpg?v=1760121861 Why Is My Isc Unstable? Ussing Chamber Drift, Noise & Baseline Fixes Why is my Isc unstable? Ussing Chamber drift, noise, and baseline fixes by Physiologic Instruments https://physiologicinstruments.com/blogs/technical/how-to-get-perfect-ussing-chamber-data 2026-06-30T09:36:06-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/EasyMount-Ussing-Chamber-System_3f31f42c-d6ef-43f1-999c-78dd3893ca01.jpg?v=1782826566 How to Get Perfect Ussing Chamber Data, <br>Fix Drift, Noise, & Leaks for Good - also via Reddit https://physiologicinstruments.com/blogs/news/epithelial-transport-explained-ussing-chamber-research 2025-11-18T11:57:24-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/epithelial-transport-powers-na-absorption_076757f8-47c6-4c33-b89a-30b7366c8d44.jpg?v=1763485044 Epithelial Transport Explained – Ussing Chamber Research Epithelial transport powers nutrient uptake, fluid balance, and barrier defense. This post explains the core mechanisms (Na+ absorption, Cl- secretion, paracellular flux). https://physiologicinstruments.com/blogs/informational/how-electrophysiology-unlocks-epithelial-transport-insights 2025-11-18T12:05:43-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/epithelial-cells-forming-a-polarized-barrier_87d2f91a-d98f-4979-9883-b75ed42c2a81.jpg?v=1763485543 How Electrophysiology Unlocks Epithelial Transport Insights Illustration of epithelial cells forming a polarized barrier with ion channels and pumps across apical and basolateral membranes, showing Na⁺ and Cl⁻ movement and electrical potential gradients. https://physiologicinstruments.com/blogs/news/sistema-a-camera-di-ussing-guida-completa-per-ricercatori 2025-11-18T12:03:29-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Camera-di-Ussing_a60662c4-5161-45c5-9a52-ef37b30ea4ea.jpg?v=1763485409 Sistema a Camera di Ussing: Guida Completa per Ricercatori Sistema a Camera di Ussing: La Guida Completa (Principi, Protocolli, Risoluzione Problemi e Selettore Prodotti) https://physiologicinstruments.com/blogs/news/how-ussing-chamber-systems-help-aquafeed-teams-optimize-nutrient-absorption 2025-11-18T12:02:43-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/ussing-chamber-fish-feed-nutrient-absorption-vs-composition_625af227-c69e-438b-86a9-fdec12dddee6.jpg?v=1763485363 How Ussing Chamber Systems Help Aquafeed Teams Optimize Nutrient Absorption Scientific illustration comparing fish feed composition versus nutrient absorption across the intestinal wall, measured using Ussing chamber systems by Physiologic Instruments. https://physiologicinstruments.com/blogs/news/cftr-electrophysiology-evolution 2025-11-18T11:36:50-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/cftr-ion-transport-in-research_a763da90-012b-44f6-8833-3ad702e1222e.jpg?v=1763483810 The Next Evolution in CFTR Electrophysiology Advanced CFTR research laboratory showing chloride transport data and CFTR protein visualizations on a computer workstation, representing progress in electrophysiology, ion-channel analysis, and modern cystic fibrosis science. https://physiologicinstruments.com/blogs/informational/ussing-chambers-vs-teer-plates-when-and-why-to-use-each 2025-12-08T13:53:36-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/ussing-chambers-vs-teer-plates_94d6bea0-f8ad-45a2-9d4b-cbfa22ba33f7.jpg?v=1765220016 Ussing Chambers vs. TEER Plates: When and Why to Use Each Diagram comparing an Ussing chamber and a TEER plate, showing epithelial layers, apical and basolateral compartments, and simplified electrodes measuring ion transport and barrier resistance. https://physiologicinstruments.com/blogs/technical/how-ag-agcl-electrodes-work-in-ussing-chamber-experiments 2025-12-24T10:15:15-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/Ag-AgC-electrodes_215e6612-f60e-438a-8d26-265db7f06680.jpg?v=1766589315 How Ag/AgCl Electrodes Work in Ussing Chamber Experiments Abstract scientific illustration symbolizing Ag/AgCl electrode chemistry and electrophysiology measurements https://physiologicinstruments.com/blogs/informational/teer-plates-vs-franz-diffusion-cells-vs-ussing-chambers 2025-12-18T14:21:00-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/teer-vs-franz-diffusion-vs-ussing-chamber-comparision_29417726-6fcf-4643-a844-078a1868b539.png?v=1766085660 TEER Plates vs Franz Diffusion Cells vs Ussing Chambers Comparison of epithelial barrier testing methods showing TEER electrical resistance measurement, Franz diffusion molecular permeability across skin, and Ussing chamber active ion transport across epithelial tissue https://physiologicinstruments.com/blogs/news/teer-platten-vs-franz-diffusionszellen-vs-ussing-kammern 2025-12-19T12:24:41-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/teer-vs-franz-diffusion-vs-ussing-chamber-comparision_e317a9b3-6daa-40f1-9ed7-d20164a00968.png?v=1766165081 TEER-Platten vs. Franz-Diffusionszellen vs. Ussing-Kammern https://physiologicinstruments.com/blogs/technical/how-to-tell-a-real-transport-effect-from-an-experimental-artifact 2025-12-29T10:40:06-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/difference-between-a-real-biological-transport-signal-and-an-experimental-artifact-in-epithelial-electrophysiology_86e89039-4cd5-4127-af47-38cceef06a93.jpg?v=1767022806 How to Tell A Real Transport Effect From an Experimental Artifact Diagram comparing a real biological transport signal and an experimental artifact in epithelial electrophysiology, showing a step-like current response with a stable plateau versus a drifting, unstable signal caused by measurement effects https://physiologicinstruments.com/blogs/technical/which-ussing-chamber-system-should-i-buy 2025-12-29T16:09:24-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/which-ussing-chamber-system-should-i-buy_87ecde8f-e0aa-4a16-8fe6-e49c436bdf17.jpg?v=1767042564 Which Ussing Chamber System Should I Buy? Which Ussing chamber system should I buy? Infographic showing Physiologic Instruments EasyMount 8-channel Ussing chamber system with EasyMount sliders and Acquire & Analyze data acquisition for clean, stable traces. https://physiologicinstruments.com/blogs/informational/best-ussing-chamber-buffers-and-gassing-2026-bicarbonate-vs-hepes-co-control-osmolarity-and-ph-stability 2026-02-02T16:56:32-05:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/bicarbonate-vs-hepes_64348e74-2dd0-4133-947e-9df5635902ac.jpg?v=1770069392 Best Ussing Chamber Buffers and Gassing (2026): Bicarbonate vs HEPES, CO₂ Control, Osmolarity, and pH Stability Two bottles: One is bicarbonate and other is HEPES buffer next to gas regulator tubing, illustrating buffer and gassing control for Ussing chamber experiments https://physiologicinstruments.com/blogs/informational/when-stable-teer-still-means-failing-tissue 2026-03-12T09:13:41-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/TEER-When_stable_teer_still_means_failing_tissue.png?v=1773321221 When Stable TEER Still Means Failing Tissue Stable TEER trace beside a colorful epithelial tissue illustration, showing that a steady electrical signal can mask underlying tissue stress or loss of function. https://physiologicinstruments.com/blogs/informational/how-electrode-noise-mimics-channel-activation 2026-03-12T11:38:48-04:00 weekly https://cdn.shopify.com/s/files/1/0653/7530/5944/articles/how_electrode_noise_mimics_channel_activation_3eb896ab-64ac-4083-a73f-30ad4deebab9.jpg?v=1773329928 How Electrode Noise Mimics Channel Activation Colorful scientific illustration showing a noisy electrophysiology trace that resembles activation, contrasted with stable epithelial tissue to represent electrode artifact mistaken for biological response.