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The P2300 EasyMount Ussing Chamber is designed as a versatile and reliable instrument for experimental research focused on transport and barrier functions of biological tissues and cell monolayers. It incorporates an intuitive design that accommodates a broad range of sample types, from native animal tissues to cultured cell layers on permeable supports, with straightforward integration into both standard and customized laboratory workflows. Equipped with precision-engineered EasyMount Ussing Chamber slider inserts, the P2300 simplifies the setup and alignment of samples, minimizing handling time and enhancing reproducibility, crucial for consistent results across ussing chamber experiments.

The ussing chamber’s flexibility in half-chamber volume (2.0–7.0 ml) allows researchers to tailor the setup to specific experimental needs, optimizing resources while maintaining accuracy. With durable construction materials suited for frequent use and compatibility with various physiological measurement devices, our ussing chamber - model P2300 is not only adaptable but also built to last, supporting the rigorous demands of high-quality research in physiology, pharmacology, and related fields.

The Corning Transwell Snapwell has become a mainstay for growing epithelial cells. Its large area (1.12 cm2) and shallow depth are ideal for transport and electrophysiological research in the EasyMount Ussing chamber. The P2302 EasyMount Slider is designed to securely hold these inserts without stress on the membrane and to position the membrane perfectly between the two halves of the P2300 Ussing chamber.

The mounting procedures for placing the Snapwell into the P2302 slider and then into the chamber are both easy and fast. The Snapwell is removed from the culture dish, separated from its holder, drained of media, and placed with its basal side against the red O-ring in the P2302 slider. Wipe the end and sides of the slider to remove any saline and “slide” the Snapwell+P2302 in the slot between the two chamber halves until it reaches the hard stop. Turn the thumbscrew on the chamber to gently squeeze the chamber halves together. Only light pressure between the chamber halves and the slider is required to make a watertight seal. Excessive pressure can distort the culture membrane and alter the electrical parameters. The procedure for mounting the tissue takes less than 30 seconds to accomplish. This system is ideal for transport and electrophysiological measurements. The P2302 enables effortless transfer of confluent cell layers directly into EasyMount Ussing Chambers, providing researchers with a streamlined, effective solution for high-quality results.

The P2306B Ussing Chamber Slider offers a solution for researchers working with small, delicate tissue samples, such as mouse trachea, in high-resolution electrophysiological studies. With a compact 3.5 x 1.8mm frame and a carefully calibrated aperture area of 0.057 cm², this chamber slider enables researchers to obtain accurate, controlled measurements of ion transport, tissue permeability, and other physiological parameters from a precisely defined tissue area. Designed to integrate seamlessly with the EasyMount P2300 Chamber system, the P2306B Slider supports stable, reproducible experimental conditions essential for in-depth tissue analysis and consistent data collection, ultimately enhancing the quality of your research outcomes.

The P2307C EasyMount Ussing Chamber Slider is a precise and efficient accessory for the P2300 Ussing Chamber System, ideal for human biopsy studies, including duodenal, colonic, and rectal samples. Its 1.5 mm diameter circular aperture, covering a focused area of 0.017 cm², allows for detailed measurement of ion transport and barrier function within small, targeted tissue sections.

The EasyMount design facilitates quick, secure mounting without pins, preserving sample integrity. In combination with the P2300 system, the P2307C Slider ensures stable and reproducible conditions, making it a valuable tool for high-resolution epithelial research on biopsy specimens.