EasyMount® Ussing Chamber Systems from Physiologic Instruments Drive Advances in Cystic Fibrosis Research

Venice, FL — August 18, 2025— Physiologic Instruments, a global leader in epithelial transport research equipment, announces the impact of its EasyMount® Ussing Chamber Systems in breakthrough cystic fibrosis (CF) research. These precision-engineered systems enable scientists to measure CFTR function, providing the reliable, reproducible data needed to advance CF drug discovery and development.

Why Ussing Chambers Matter in CF Research

The Ussing Chamber technique is the gold standard for quantifying chloride ion transport across epithelial tissues — a critical measure in cystic fibrosis research. By accurately assessing CFTR activity and chloride transport, researchers can evaluate the effectiveness of new CF therapies.

Physiologic Instruments’ EasyMount® Ussing Chamber System delivers:

• Clean, stable short-circuit current recordings

• Optimized chamber design for reproducible results

• Reliable Ag/AgCl electrode performance

• Streamlined setup that reduces time and variability

“Accurately measuring CFTR rescue requires more than just sensitive equipment — it requires confidence that every reading is reliable,” said a spokesperson for Physiologic Instruments. “Our EasyMount® Ussing Chambers are designed to deliver consistent, artifact-free data, giving researchers the clarity they need to advance therapies for cystic fibrosis.”

 

Powering Breakthrough Discoveries

The EasyMount Ussing Chamber has supported research that contributed to the development of modern CFTR modulators — a class of therapies that improve lung function and quality of life for people with cystic fibrosis. By providing confidence in CFTR measurement, the system has become an essential tool for academic labs, pharmaceutical companies, and translational research centers.

For example, recent studies cited the use of Physiologic Instruments’ Ussing Chambers in evaluating ion transport and epithelial barrier function, further cementing their importance in both basic and applied CF research.

Beyond Cystic Fibrosis

While central to CF research, EasyMount® Ussing Chamber Systems are also used in studies of:

• Intestinal permeability and drug absorption

• Airway epithelial transport

• Barrier function in gastrointestinal, renal, and pulmonary models

This flexibility makes the platform a cornerstone for laboratories investigating epithelial physiology and drug development worldwide.

Learn More

To explore the role of Physiologic Instruments Ussing Chambers in cystic fibrosis research, visit the full press release on PRLog:
👉 https://www.prlog.org/13093519-physiologic-instruments-ussing-chambers-aid-key-cystic-fibrosis-research.html

 

About Physiologic Instruments

Physiologic Instruments designs and manufactures specialized research equipment for epithelial transport and barrier function studies. With decades of innovation, its products — including the EasyMount® Ussing Chamber Systems, voltage-current clamps, and data acquisition tools — are trusted worldwide for their accuracy and reliability.