Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control
Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control
Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control
Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control
Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control
Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control

Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control

Designed for Transepithelial Electrophysiology Data Acquisition

ACQUIRE & ANALYZE is a specialized data acquisition and analysis system for measuring bioelectrical properties in epithelial tissues or cell layers on permeable membranes, used with VCC MC2, MC6, or MC8 voltage/current clamps. Designed specifically for transepithelial electrophysiology, it records and plots voltage, current, and transepithelial resistance (TEER) in real time from up to eight tissues, eliminating the need for post-processing to calculate TEER. The Windows®-based software provides an intuitive interface, allowing users to set parameters, select data collection rates, and generate compact files with minimal effort. By combining hardware, cables, and optimized software, it simplifies and enhances electrophysiological measurements for targeted research applications.
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// Zero Price Product Handler for HubSpot Quote Integration document.addEventListener('DOMContentLoaded', function() { console.log('Zero price handler loaded'); // Initialize HubSpot forms immediately function initHubSpotForms() { console.log('Checking for HubSpot...'); // Check if HubSpot is loaded if (typeof hbspt !== 'undefined' && hbspt.forms) { console.log('HubSpot found, initializing forms...'); const formContainers = document.querySelectorAll('.hs-form-frame[data-form-id]'); console.log('Found form containers:', formContainers.length); formContainers.forEach(container => { const formId = container.getAttribute('data-form-id'); const portalId = container.getAttribute('data-portal-id'); const productTitle = container.getAttribute('data-product-title'); console.log('Creating form:', formId, portalId); // Create the form hbspt.forms.create({ region: "na2", portalId: portalId, formId: formId, target: container, onFormReady: function(form) { console.log('Form ready!'); // Hide fallback button const fallbackBtn = document.querySelector('.button-quote-request'); if (fallbackBtn) { fallbackBtn.style.display = 'none'; } }, onFormSubmit: function(form) { console.log('Form submitted'); } }); }); } else { console.log('HubSpot not loaded yet, retrying...'); // Retry after a delay setTimeout(initHubSpotForms, 1000); } } // Start initialization initHubSpotForms(); // Also try when window fully loads window.addEventListener('load', function() { setTimeout(initHubSpotForms, 500); }); });

Product Description

Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control

Acquire & Analyze 3 — Multi-Channel Data Acquisition & Integrated pH Control

Acquire & Analyze 3 is our next-generation acquisition platform for Ussing chamber and epithelial transport research. Run up to 8 channels simultaneously, control the pH EpiStat titrator in closed loop, and capture synchronized ISC, Rt, pH, and voltage data with automated event logging and continuous backup.

Key Features

  • 8 Independent Channels: Simultaneous acquisition with synchronized traces (ISC, Rt, pH, Voltage).
  • Integrated pH Control: Built-in closed-loop control with the pH EpiStat titrator—no external software required.
  • Real-Time Adjustments: Change gain, offsets, and apply references per channel without interrupting acquisition.
  • Automated Event Logging: Titrations, voltage steps, annotations, and calibration steps are timestamped and saved automatically.
  • Guided Calibration Wizard: Streamlined electrode and amplifier standardization for consistent cross-channel data.
  • Multi-Threaded Graphing Engine: Smooth live plotting and responsive controls during long experiments.
  • Continuous Auto-Save: Redundant background saving to protect long recordings.
  • Backwards Compatibility: Works with EasyMount P2300/P2400 chambers and the VCC MC8 amplifier.
  • Flexible Exports: CSV/TXT plus optional PDF summaries with event overlays and embedded metadata.

What’s New in Version 3

Area New in A&A 3
Throughput Expanded from 4 to 8 simultaneous channels.
pH Control Integrated closed-loop pH via pH EpiStat with refined PID behavior and minimal overshoot.
Workflow Unified ribbon for VCC + titrator control; real-time per-channel adjustments without stopping.
Calibration New Calibration Wizard with stepwise guidance and automatic verification.
Data Integrity Continuous auto-save, recovery prompts, and detailed event/metadata embedding.
Visualization Multi-threaded plotting, synchronized cursors, event overlays, and faster refresh.

Technical Highlights

  • Unified Control Surface: Amplifier and titrator controls live in one interface with live status indicators (RUN/STOP/SYNC).
  • Synchronized Event Markers: Titration additions and reference changes appear inline on traces with timestamps.
  • Channel-Specific Gain & Reference: Adjust per channel on the fly; global reference application supported.
  • Lower Baseline Noise: Improved stability and drift handling across long runs.
  • Metadata-Rich Exports: Chamber IDs, tissue notes, slider IDs, titration events and timing included in output files.
Acquire & Analyze 3 - Multi-Channel Data Acquisition & Integrated pH Control

Scientific & Operational Advantages

  1. Higher Throughput: True 8-channel acquisition enables parallel conditions and replicates.
  2. Better Reproducibility: Closed-loop pH, guided calibration, and synchronized event logging improve repeatability.
  3. Time Efficiency: Real-time adjustments eliminate stop-and-restart interruptions.
  4. Traceability: Automatic audit trail of interventions, titrations, and annotations per channel.
  5. Data Security: Continuous auto-save protects long recordings and multi-hour studies.

What is NEW! — At a Glance

Category Acquire & Analyze 2 Acquire & Analyze 3
Channel Capacity Up to 4 Up to 8
pH Control External/manual Integrated closed-loop (pH EpiStat)
Gain/Reference Adjust Pause required Real-time, per-channel
Calibration Separate utility In-app wizard with verification
Event Logging Manual markers Automated, timestamped feed
Data Integrity Manual saves Continuous auto-save & recovery
Graphing Engine Legacy single-threaded Multi-threaded, high-refresh

Technical Specifications

Supported Channels Up to 8 simultaneous channels
Signals ISC, Rt, pH, Voltage (per channel)
Sampling Up to ~200 sps/channel (typical operating range; project-dependent)
pH Control Integrated pH EpiStat titrator (closed-loop, PID-based)
Calibration In-app wizard for electrodes & amplifier channels
Export Formats CSV, TXT, optional PDF summaries with event overlays
OS Compatibility Windows 10/11 (64-bit)
Connectivity USB 2.0 or Ethernet (device-dependent)
Supported Hardware VCC MC8 amplifier; EasyMount P2300/P2400 chambers; pH EpiStat titrator

Compatibility & What’s Included

  • Compatibility: EasyMount P2300/P2400, VCC MC8, pH EpiStat titrator.
  • Included: A&A 3 software license, user guide, and quick-start calibration checklist.
  • Optional: Training session with our applications team; remote setup assistance.

Frequently Asked Questions

Can I run 8 channels and pH control at the same time?

Yes. A&A 3 is designed to acquire up to 8 channels while operating the pH EpiStat titrator in closed loop. Event markers record pH corrections alongside all traces.

Do I need to pause acquisition to adjust gain or apply a reference?

No. You can perform per-channel gain/offset changes and apply references during acquisition.

What export formats are available?

CSV/TXT with embedded metadata and event timing; optional PDF summaries with event overlays for reports.

Is A&A 3 compatible with my existing Physiologic Instruments hardware?

Yes. A&A 3 supports the VCC MC8, EasyMount P2300/P2400, and the pH EpiStat titrator.

Customer Reviews