Ussing Chamber Systems for Epithelial Transport & CFTR Research

Build your Ussing chamber workflow with precision chambers, complete systems, and voltage/current clamps—optimized for SCC, TEER, and ion transport studies. Expert U.S. support and worldwide delivery.

Browse Ussing Systems, compatible ussing chambers, and accessories—or request a quote.

Ussing Chamber Systems in the laboratory. Physiologic Instrument's EasyMount Ussing Chamber System

Physiologic Instruments designs and manufactures Ussing Chamber Systems and instrumentation. Our EasyMount Ussing Chamber Systems and Data Acquisition products for epithelial transport research. Bioelectrics such as transepithelial voltage, short-circuit current and resistance or conductance are measured using single and multi-channel voltage/current clamps that may be directly connected to Acquire and Analyze for automating data collection and analysis. Our EasyMount Ussing chambers provide solutions for labs wanting to study different types of epithelial tissues and cell cultures in a single chamber system that offers ease of use, easy cleanup and exceptional flexibility.

Physiologic Instruments is a leader in ussing chamber equipment for epithelial barrier research. Some applications: Cystic Fibrosis Research, Electrophysiology, Pathophysiology, Nutrition, Flux Studies, Permeability Studies, Drug Transport, Drug Screening, Toxicology, Pharmacology, Immunology, Parasitology, Cell Biology, & Many More. - Made in the USA.



NEW! pH EpiStat for Ussing Systems

pH Epistat with automated titrator to measure changes in pH from either the apical or serosal chamber
pH Epistat Module pH8 with automated titrator to measure changes in pH from either the apical or serosal chamber

pH Epistat for Ussing Systems Precise pH & Bioelectric Data

Epithelial cells lining the intestinal and airway tracts play a crucial role in regulating luminal pH, which is essential for maintaining tissue homeostasis, protecting against damage, and supporting proper physiological functions such as digestion, absorption, and host defense. In the intestine, epithelial cells modulate luminal acidity through coordinated acid and base secretion via specialized ion transporters on their apical and basolateral membranes. Likewise, airway epithelial cells tightly control the pH of the airway surface liquid to optimize mucociliary clearance, antimicrobial activity, and overall lung health.

The pH epiStat system provides researchers with an accurate and convenient means to quantify acid and base transport rates across epithelial tissues. By integrating with our advanced voltage and current clamp technologies, it simultaneously measures bioelectrical properties, enabling comprehensive studies of epithelial ion transport mechanisms underlying pH regulation.

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Multi-Channel Ussing Chamber Equipment


P2300 EasyMount Ussing Chamber Sliders

Unlock the power of precise epithelial barrier research with Physiologic Instruments and their Ussing Chamber Systems. Our innovative equipment delivers fast and reliable results for drug discovery, drug transport and other studies in electrophysiology, pathophysiology, nutrition, immunology, parasitology and more. Physiologic Instruments and Ussing Chambers At Physiologic Instruments, we wouldn't be able to provide the innovative epithelial research solutions we do today without the extraordinary findings of Dr. Hans H. Ussing, the inventor of the original Ussing Chamber over 70 years ago. His revolutionary research illuminated the way ions were actively transported across frog skin, leading to highly accurate analyses of the intestine, kidney, respiratory epithelia, and exocrine glands. Now, Physiologic Instruments is proud to be the epithelial research innovator that has taken Ussing's original invention and advanced it to the next level, through many advancements in Ussing Chambers and other technologies.



Since 1981

Universities & Companies all over the world have trusted Physiologic Instruments Ussing Chamber Systems

See what our customers say

"Physiological Instruments supplies high-quality equipment that performs extremely well and has been invaluable to our research. Dr. Hirsh has been a great help by providing assistance and sharing his technical expertise.”

Dr Preston H

Preston - Metabolic Research

“I am very happy with the prompt assistance that I get whenever I call Physiologic instruments. I have interacted with Dr. Hirsh on three occasions regarding troubleshooting a software/computer error. He is extremely knowledgeable, patient, and ready to walk me through the process until he is satisfied with the result. I think they are doing a great job with remote assistance.”

Dr Anyesha

Anyesha - Neuroscience

“With the kind help of thier staff, the issue on the VCC MC8 in our lab is resolved. Andrew helped me with testing, and all looks good. So, thank you very much for all the support.”

Christel

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