Compare Ussing Chamber Systems: EasyMount vs. Scientific Instruments
September 15, 2025
Why Compare?
When choosing an Ussing chamber system, small design differences can have a big impact on reproducibility, ease of use, and data quality. Below is a side-by-side comparison of Physiologic Instruments EasyMount Ussing Chamber Systems and Scientific Instruments (Germany) Ussing Chamber Systems, based on published specifications and customer experience.
EasyMount Ussing Chamber Advantages at a Glance
-
Faster setup: Slider system eliminates O-rings and manual alignment.
-
More precise: PID-controlled heating ±0.1 °C.
-
Higher resolution: 16-bit A/D clamps with Acquire & Analyze software.
-
Greater flexibility: Over 12 slider options (0.01–1.26 cm²) plus specialty chambers.
-
Unique tools: Only system with pH Epistat module for acid/base transport studies.
-
Trusted worldwide: Used in epithelial transport labs from North America to Europe and Asia.
Side-by-Side Comparison
| Feature / Spec | Physiologic Instruments — EasyMount Ussing Chambers | Scientific Instruments — Ussing Chambers |
|---|---|---|
| Chamber Geometry | Wide slider library (0.01–1.26 cm²), interchangeable across chambers. Specialized for GI, renal, airway, ocular tissue. | Fixed diffusion chambers (5×10 mm, 5×8 mm, 1 cm²). Snapwell® type options. Adapter inlays required for smaller sizes. |
| Mounting Method | Patented slider system for quick, reproducible tissue prep. No O-ring maintenance. | O-ring seals, locking rings, acrylic inlays. Manual alignment required. |
| Temperature Control | Integrated jackets with PID regulation ±0.1 °C. Independent chamber monitoring. | External water bath with metal heat block. No precision specs published. |
| Voltage/Current Clamps | MC2, MC4, MC6, MC8: low noise, real-time clamp, 16-bit A/D. Acquire & Analyze software with live and batch analysis. | VCC2, VCC4, VCC6: ±400 mV / ±1000 µA, 13-bit A/D. Winclamp software with basic Excel export. |
| TEER Measurements | Direct TEER logging via clamp protocols or adapters. Continuous, automated. | External EVOM2/EVOM3 TEER meters. Manual readouts. |
| Unique Modules | pH Epistat module for real-time pH clamping. Wide specialty chambers. | None beyond diffusion chamber catalog. |
| Ease of Use | Fast prep, easy cleaning, reproducible results. | Frequent O-ring swaps, adapter changes, slower setup. |
| Support & Service | Based in Venice, FL. Global training, applications support, fast repairs. | Germany-based. Limited service info available online. |
Why Upgrade?
If your lab is looking for:
-
Less time mounting tissue
-
Better control of temperature and electrical parameters
-
Specialized modules like pH Epistat
-
Stronger global service and support
…then EasyMount Systems by Physiologic Instruments offer the clear advantage. Are you ready to move beyond O-rings and outdated clamps?
When it comes to Ussing chamber systems, the difference is clear. Physiologic Instruments’ EasyMount technology is designed to save researchers time, deliver more precise results, and open new possibilities with unique modules like the pH Epistat. By contrast, older O-ring systems with external water baths and limited software support can slow down experiments and introduce unnecessary variability.
Whether your lab focuses on gastrointestinal, renal, pulmonary, or epithelial research, EasyMount provides the flexibility, accuracy, and support you need to push your science forward. With proven performance in labs worldwide and dedicated support from our team, upgrading to EasyMount isn’t just a choice — it’s the smarter path for reproducible, high-quality research.